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The effect of six weeks of high-intensity interval training (HIIT) on serum levels of brain-derived neurotrophic factor (BDNF), depression, and antisocial personality in women undergoing drug withdrawal
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Forough Dahmardeh   , Majid Vahidian-Rezazadeh , Omid Mohammaddoost *  |
| Department of Sport Sciences, Faculty of Education and Psychology, University of Sistan and Baluchestan, Zahedan, Iran |
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Abstract: (7 Views) |
Background and Aim: Brain-derived neurotrophic factor is a marker in psychiatric disorders. The study aimed to investigate the effect of six weeks of high-intensity interval training on brain-derived neurotrophic factor levels, depression, and antisocial personality in women undergoing drug withdrawal.
Methods: The statistical population in the present semi-experimental study was women in the process of quitting traditional drug addiction, aged 30-35, in Zahedan. 20 of these women were purposefully selected and randomly assigned to two groups: high-intensity interval training and control. Six-week training protocol, three sessions per week, and included: (8-minute warm-up and four four-minute sets at an intensity of 85 to 95% of maximum heart rate; with a 3-minute rest between each set and finally, a 5-minute rest). An independent t-test was used to compare between groups, and a dependent t-test was used to examine the difference within groups using SPSS-26 with a significance level of p < 0.05.
Results: The results showed that there was a significant difference in BDNF levels (p = 0.01) and depression (p = 0.00) between the two groups at the post-test stage, but there was no difference in antisocial personality disorder and weight between the two groups at this stage (p = 0.05). There was a significant difference between the pre-test and post-test in BDNF levels, depression, antisocial personality disorder, and the weight of the subjects in each group (p = 0.00).
Conclusion: In our study, six weeks of high-intensity interval training increased BDNF levels and reduced depression in women undergoing drug withdrawal, but had no significant effect on antisocial personality traits. These results highlight the potential effectiveness of high-intensity interval training as an intervention to improve mental health outcomes in this specific population.
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| Keywords: Women recovering from addiction, Antisocial personality, BDNF, Depression, High-intensity interval training |
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Full-Text [PDF 586 kb]
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Type of Study: Original Research |
Subject:
Exercise physiology
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