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Nitric oxide and its signaling in the central regulation of food intake: a comparative study between avian and mammalian models
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Kimia Mahdavi   , Morteza Zendehdel *  , Hamed Zarei |
| Department of Basic Sciences, Faculty of Veterinary Medicine, University of Tehran, Tehran, Iran |
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Abstract: (285 Views) |
The regulation of food intake is a complex process influenced by various neurochemical signals, including hormones and neurotransmitters. This review discusses the critical role of the central nervous system in regulating food intake, focusing on the effects of nitric oxide and its interactions with neurotransmitters and hormones. Nitric oxide, as a gaseous messenger molecule, plays an important role in regulating appetite through its interactions with neurotransmitters such as neuropeptide Y, dopamine and serotonin, as well as with hormones such as leptin and ghrelin. Understanding these interactions could provide novel insights into potential therapeutic approaches for appetite-related disorders such as obesity and anorexia nervosa. Furthermore, this review highlights the current knowledge regarding the diverse mechanisms of nitric oxide effects on appetite regulation and opens new avenues for future research pathways.
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| Keywords: Food intake, Appetite, Nitric oxide, Neurotransmitters, Hormones |
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Full-Text [PDF 1082 kb]
(136 Downloads)
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Type of Study: Original Research |
Subject:
Neuroscience
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